To become a paid subscriber, begin the process by registering. How Are The Steps Of SARS-CoV-2 Infection Different From Lytic Infection Of A DNA Virus? 2.

Analyze how different antiviral therapies work. The Central Dogma. They consider the genome of SARS-CoV-2, which consists of RNA-based nucleic acids, and its mechanism of translation. Compare and contrast antibiotic and antiviral treatments.

Use resources found at either/both of the following websites to guide you in the process: • Centers for Disease Control and Prevention. It dwells in the upper respiratory tract, where it is easily sneezed or coughed onto its next victim. How are the steps of SARS-CoV-2 infection different from lytic infection of a DNA virus? This problem has been solved! < ; • National Center for Biotechnology Information. < ; 1. x��[��Fr���):z��9#������c;�xc%N��>`H�+��P�ɧO��d��XG���I�l�����˯ _���a�}K����7�ߊ�~M�}��}�G��\���=�bx����~#�Y��}��#g�Bm�c������f_���L�������i�����ӗ$��7��/^⫆����9~���N3�d7tFH�\�7�i�0��v�W�/�����M=��f�f��z�t\��~Ú݊-�ͦ�n�7��[���U)���I�q:���4��?L����pU����s�_�'}齚��0�L�I�b?t&�����ks3��e˾��ն�����o�Gŕy�p6����q$^�J�y������5�13F3Y��4�N� d�����ȓBF-�.zm}~�@��tV�G� Gt�ZH�o�^�!� �*�o��5�M�՞����@'�p�M��h�~���|�Fz;�h!R��z��N/�$OW�2�Nl�� ���>g8��mv���v�U?����m�{��S�ʅ4�Pp7 ���e���}~)RsGDe3ܵC��;�ۖ�|hǩ�w#��lK�7�]?�u�����TSA-\ �2���fX��7��*�޴nK؋K�_9�S&���JQ�:b��0��{�o���WOE�`�.깥,�|��)��Ư=�+l�șEP�t�.��A��ZL���bJe��Bk�1" ; The central dogma suggests that DNA contains the information needed to make all of our proteins, and that RNA is a messenger that carries this information to the ribosomes.

Students explore the differences between SARS-CoV-2, which causes COVID-19, and other viruses like herpes, influenza and HIV. Terms Draw the life cycle of SARS-CoV-2 and contrast it to the life cycle of a different DNA virus, herpes simplex. How are they similar? <> stream View desktop site, 2.

Lytic cycle of DNA virus The virusattaches itself to the host cell.

How Does Coronavirus Defy Traditional Models Of Central Dogma? Lytic cycle of DNA virus The virusattaches itself to the host cell. If you're stumped, don't worry.

Compare the cellular and biochemical characteristics of SARS-CoV-2, herpes simplex virus-1, HIV, and influenza B.

How does coronavirus defy traditional models of biology's central dogma? Teaching notes are intended to help teachers select and adopt a case.

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They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources. The tip of the tail produces a hole in the bacterial cell by means of enzyme lysozyme.

Understand the importance and ethics of sharing personal information about disease. What are some potential complications to this infection strategy? How might an RNA-based genome result in an increased infection rate?

This new coronavirus, SARS-CoV-2, adeptly cuts the difference. All Rights Reserved. How does coronavirus defy traditional models of central dogma? & 2. What is the central dogma of biology? The central dogma is not really a dogma in the traditional sense of the word, like all scientific theories it is modified as we learn more details of the processes. 15 0 obj This states that once "information" has passed into protein it cannot get out again. Case teaching notes are password-protected and access to them is limited to paid subscribed instructors.

It was first stated by Francis Crick in 1957, then published in 1958:. The tip of the tail produces a hole in the bacterial cell by means of enzyme lysozyme. The central dogma of molecular biology is an explanation of the flow of genetic information within a biological system. endobj © 1999-2020 National Center for Case Study Teaching in Science, University at Buffalo. How does coronavirus defy traditional models of central dogma? How are the steps of SARS-CoV-2 infection different from lyric infection of a DNA virus? 14 0 obj

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The case concludes with a writing assignment in which students use what they have learned in the case and address ethical questions involved with sharing patient information.

Answer keys for the cases in our collection are password-protected and access to them is limited to paid subscribed instructors. �0FG�s�Ζ��`��b��q!��*����< �R�G�Z �p�s/�XJ�E�ǭ�: Compare the efficacy of both when treating COVID-19. It is often stated as "DNA makes RNA, and RNA makes protein", although this is not its original meaning. Fill in the table below comparing four different viruses. This directed case study was designed for introductory level or mid-level biology students to serve as a capstone project incorporating aspects of nucleic acid, lipid and protein structure and function, central dogma, and virus life cycles. %PDF-1.7 Attachment- the phage attaches to the surface of the host. © 2003-2020 Chegg Inc. All rights reserved. DNA Central Dogma Part 1 - Transcription Embedded video for DNA Central Dogma Part 1 - Transcription These molecular animations were created for a major trans-national production effort to raise awareness, educate and promote DNA science to the wider community, coinciding with the 50th anniversary of the discovery of the double helix. This directed case study was designed for introductory level or mid-level biology students to serve as a capstone project incorporating aspects of nucleic acid, lipid and protein structure and function, central dogma, and virus life cycles. What are some potential complications to this infection strategy? )�m�j�cGiéE0�� �c��$���h��&Ob.

They examine the structure of SARS-CoV-2 and how it binds to and enters a cell.

The storyline follows two young girls and their family during the 2019–2020 coronavirus outbreak in the United States. The storyline follows two young girls and their family during the 2019–2020 coronavirus outbreak in the United States. (Answers are below.) 5. 4. The central dogma of molecular biology explains the flow of genetic information, from DNA to RNA, to make a functional product, a protein. Students then research the mechanism of action of these antivirals, suggest why they will not be successful in treating COVID-19, and predict possible antiviral targets specific for SARS-CoV2.

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4. See the answer. One of the girls in the story tests positive for COVID-19 and her parents consider multiple antiviral treatments approved for influenza, HIV and herpes. %���� Describe the structural characteristics of the SARS-CoV-2 virus. How might an RNA-based genome result in an increased infection rate?

3. | Privacy 3. Show transcribed image text. What is the central dogma of biology? How are they similar?



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